Tuesday, 20 May 2014

Eladur (Neuropathic Pain) - Forecast and Market Analysis to 2022



Summary


Neuropathic pain (NP) is defined as a disorder of the sensorimotor system and is distinctly different from nociceptive pain, which is a consequence of trauma, injury, or inflammation. The main difference between neuropathic and nociceptive pain is the absence of a continuous nociceptive input in neuropathic pain. Although the term neuropathic pain is used to describe a wide range of pain syndromes with varying etiologies, this report focuses on 3 distinct forms of NP: Painful diabetic neuropathy, Postherpetic neuralgia and trigeminal neuralgia. The main classes of drugs used to treat these three neuropathic pain indications include anticonvulsants, antidepressants, opioids and topical treatments. However, despite the availability of multiple pain medications only 50% of patients respond to any given drug and there are numerous the side effects associated particularly with systemically administered drugs, that reduce their tolerability.



New treatments will target some key unmet needs in terms of efficacy and tolerability, but opportunities will remain for drugs that can more reliably eradicated NP in targeted patient populations, as well as offering an improved safety profile.

Eladur is a transdermal bupivacaine patch developed by Durect Corporation that is intended to deliver bupivacaine for up to three days from a single application. Durect had been engaged in a licensing agreement with Pfizer (through its subsidiary, King Pharmaceuticals) to develop and commercialize Eladur, but in February 2012, Pfizer notified Durect that it was terminating this agreement and returned all the rights to Durect. In January 2014, Durect established another development and commercialization agreement for Eladur, this time with Impax Laboratories.

Scope

- Overview of Neuropathic pain, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
- Detailed information on Eladur acetate including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for Eladur acetate for the top six countries from 2012 to 2022.
- Sales information covered for the US, France, Germany, Italy, Spain and the UK.


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Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return
- Stay ahead of the competition by understanding the changing competitive landscape for Neuropathic pain
- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
- Make more informed business decisions from insightful and in-depth analysis of Eladur acetate performance
- Obtain sales forecast for Eladur acetate from 2012-2022 in the top six countries (the US, France, Germany, Italy, Spain and the UK).


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